Xiaflex – A New Drug To Reduce Penile Curvature By Injections

A new drug has been developed in America for men with Peyronie’s disease. Auxilium Pharmaceuticals, who are the manufacturers of the product, claim that it can cure patients from that uncomfortable condition that causes their penis to curve when erect, so much so that it makes sexual intercourse painful.

Around 5-10% of men are affected by Peyronie’s disease, however only a small portion of them have a more serious form of it. The condition can be caused by practicing vigorous sex that causes trauma and scar tissue build-up in the male organ. The new Xiaflex treatment can break this scar tissue down, reducing curvature.

Xiaflex was first created for treating Dupuytren’s contracture (patients can’t straighten their fingers), it involves injections and surgery that also comes with some risk of injury. That is why FDA only lets physicians who are well trained to use this method.

Until today, surgery was the main and most effective option for the sufferers of Peyronie’s disease. Unfortunately that often comes with side effects such as erectile dysfunction or shortening of the penis.

Peyronie’s disease, which got its name after F. G. de la Peyronie who was the physician to first describe it, has a number of other treatment methods, including stretching, injections, use of vacuum devices, laser surgery and electrical treatments. The condition is often hard on the sufferers who feel depressed because it’s hard for them to engage in sexual activities.

Ryan Berglund, a urologist at the Cleveland Clinic said that while we may joke about the issue, for a person in a relationship or trying to establish one, not being able to perform sexually is a very serious problem.

Xiaflex will only be recommended for those whose curvature is over 30%, however, it is not a cheap treatment – the price for the 8 necessary injections will be around $3,300. Still, after Auxilium announced tat their trials had been successful, their shares went up in the market.

Other medical experts remain cautious since Xiafles will not completely remove the problem, it will only reduce the curvature of the penis. James Tursi from Auxilium advised that after treatment, men should not have sex for at least two weeks.


  1. surgery is the last option in treatment Peyronie’s

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